Eugenol molecular docking breast cancer
Webeugenol compounds to the receptor target in breast cancer. The method used is molecular docking using Autodock Vina software. The results showed that eugenol compounds can interact with ER-α, ER-β, and HER-2 and have the potential as breast anticancer with the best binding affinity based on the observed RMSD value. Keywords: … WebJan 1, 2024 · The hyper activity of estrogen hormone may potentially lead to the multiplication of the ER-α in the mammalian cells which lead to maintenance and growth of types of breast cancers, and also holds various molecular targets for …
Eugenol molecular docking breast cancer
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WebMay 15, 2024 · Design, synthesis and molecular docking studies of thymol based 1,2,3-triazole hybrids as thymidylate synthase inhibitors and apoptosis inducers against breast … WebJan 1, 2024 · Estrogens play a central role in breast cancer improvement with ERα status being the mainly significant predictor of breast cancer prognosis. The potent lead …
WebEugenol, now finds its application as potential anti-cancer compound. It has been observed to induce apoptosis of various cancer cells and cause the modulation of the cell cycle pathway. However the exact mechanism is yet to be studied. WebFeb 8, 2024 · Breast cancer occurs due to uncontrolled cells proliferation. The Proliferation causes severe inflammatory which can be the initial stages of cancer symptoms. Aryl amino alcohol compounds from isoeugenol derivatives are …
WebDec 6, 2024 · Several studies have displayed diverse molecular pathways for varied cura-tive mechanisms of eugenol in the treatment of various cancer types [23–27]. ... and eugenol cancer types between the years 2010 and September 2024 to prepare the current review. 3. Eugenol Characteristics Eugenol (4-allyl-2-methoxyphenol; C10H12O2) is … WebJun 25, 2024 · G Protein-Coupled Receptor 116 is an adhesion orphan receptor that intensifies the invasion of cells in Triple-Negative Breast Cancer. In this study, existing …
Web•Screened against MCF-7 breast cancer cells for their anti-cancer activity by measuring the cytotoxicity. ... Thus molecular docking and molecular dynamics (MD) simulation experiments were executed to validate our hypothesis on mode of ligands binding and protein complex stability. ... Eugenol is a natural product abundantly found in clove ...
WebApr 28, 2024 · Meanwhile, cervical cancer cells showed the highest predicted protein binding to IL-10 and MAPK3 with a docking score of -10.5 and -10.8 kcal/mol. The docking score of molnupiravir against the COVID-19 virus protein, AGTR2, and ENPEP were -7.4 and -7.2 kcal/mol, respectively. cricket funny clips youtubeWebThe binding capacities of eugenol to conservative sites of SARS-CoV-2 like RNA-dependent RNA polymerase (RdRp) and mutable site as spike (S) protein, were calculated by using molecular... cricket game 2007 free download softwareWeb- 123doc - thư viện trực tuyến, download tài liệu, tải tài liệu, sách, sách số, ebook, audio book, sách nói hàng đầu Việt Nam cricket game 2013 free download for pcWebJul 1, 2024 · We have screened various phytochemicals (mostly enriched in essential oil) of basil to define their role in breast cancer using molecular docking studies. These studies were against... cricket gambling websiteWebThe molecular docking approach is carried out to see the interaction of ligands with protein compounds by using the minimized ligand energy bind with protein active site using … cricket game 2010 torrentWebJan 17, 2003 · Eugenol also induced autophagy by upregulating the expression levels of microtubule-associated protein 1 light chain 3 (LC3) and downregulating the expression … budget and cost loadingWebOct 26, 2024 · Eugenol is thought to help cisplatin suppress breast cancer stem cells by hindering the action of aldehyde dehydrogenases (ALDH) and ALDH-positive cancer beginning cells, as well as... budget and costing in project management